The team, trained by Ugandan Jackson Mayanja will top the 16-team league if they win the game to be staged at the Kambarage Stadium as they will have 45 points.
The Msimbazi Street side are currently placed second with 42 points while defending champions Yanga lead the pack on 43 points.
The Simba head coach said that they will play speedy attacking football to make sure they pocket three points from the home side.
The team will leave for Morogoro to prepare for their next game against archrivals Yanga set for next Saturday at the National Stadium in Dar es Salaam.
Yanga plans to camp in Zanzibar after playing away Cercle de Joachim SC in an African Champions League preliminary round, first leg match today in Curepipe, Mauritius.
Other league matches set for today.
Mgambo vs African Sports
Mbeya City vs Toto Africans
Ndanda FC vs Majimaji
JKT Ruvu vs Kagera Sugar
Tomorrow
Mwadui vs Tanzania Prisons
Coastal Union vs Azam FC
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